Case report: New insights into persistent chronic pelvic pain syndrome with comorbid somatic symptom disorder.

Chronic pelvic pain syndrome (CPPS) is generally defined as pain in the pelvic area that persisted for 3-6 months or longer. The pain can be constant or episodic and functionally disabling. Any dysfunction of the central nervous system can lead to central sensitization, which enhances and maintains pain as well as other symptoms that are mediated by the central nervous system. It occurs in subgroups of nearly every chronic pain condition and is characterized by multifocal pain and co-occurring somatic symptoms. Somatic symptom disorder (SSD) is defined as a condition in which having one or more somatic symptoms, such as excessive worries, pressure, and catastrophic events. These symptoms can be very disruptive to a patient's life and can cause significant distress. SSD cases with severe symptoms frequently undergo repeated medical investigations and the symptoms often lead patients to seek emergency medical treatment and consult with specialists repeatedly, which is a source of frustration for patients and clinicians. Here we report a case that Asian female with persistent CPPS with comorbid SSD, who got in trouble for up to 8 years. This case reminds clinicians to pay excessive attention to the diagnosis of CPPS with comorbid SSD after recovery from acute COVID-19, with hope of raising awareness in the identification of SSD and present new insight into appropriate treatment for each woman who suffers from it.

Case report: New insights into persistent chronic pelvic pain syndrome with comorbid somatic symptom disorder

Chronic pelvic pain syndrome (CPPS) is generally defined as pain in the pelvic area that persisted for 3–6 months or longer. The pain can be constant or episodic and functionally disabling. Any dysfunction of the central nervous system can lead to central sensitization, which enhances and maintains pain as well as other symptoms that are mediated by the central nervous system. It occurs in subgroups of nearly every chronic pain condition and is characterized by multifocal pain and co-occurring somatic symptoms. Somatic symptom disorder (SSD) is defined as a condition in which having one or more somatic symptoms, such as excessive worries, pressure, and catastrophic events. These symptoms can be very disruptive to a patient's life and can cause significant distress. SSD cases with severe symptoms frequently undergo repeated medical investigations and the symptoms often lead patients to seek emergency medical treatment and consult with specialists repeatedly, which is a source of frustration for patients and clinicians. Here we report a case that Asian female with persistent CPPS with comorbid SSD, who got in trouble for up to 8 years. This case reminds clinicians to pay excessive attention to the diagnosis of CPPS with comorbid SSD after recovery from acute COVID-19, with hope of raising awareness in the identification of SSD and present new insight into appropriate treatment for each woman who suffers from it.

Addressing psychosomatic issues after lifting the COVID-19 policy in China: A wake-up call.

The Coronavirus has infected up to 900 million people as of 11 Jan 2023 in China Mainland, which is more than 60% of the population. The sudden and unprecedented nature of pandemic has resulted in a range of psychosomatic issues among the population. These issues can manifest in a variety of ways and it is important to address these issues as they can have serious consequences for individuals' mental and physical health. The lifting of lockdown measures in China presents an opportunity to address these issues and provide support to those who have been affected.

Pharmaceuticals and Personal Care Products across Different Water Bodies in Taihu Lake Basin, China: Occurrence, Source, and Flux.

Although pharmaceuticals and personal care products (PPCPs) have attracted great attentions, their occurrence characteristics across different water bodies at a basin scale remain poorly understood. To grasp a more comprehensive understanding of PPCP pollution from the perspective of the whole basin, the occurrence, spatial and seasonal variation, source, and flux of thirteen PPCPs across the different environmental compartments of the northern Taihu Lake Basin (TLB) were studied. The results showed that the non-therapeutic pharmaceuticals caffeine (CFI) and n, n-diethyl-m-toluamide (DEET) were the main components across the different environmental compartments. The total concentrations of detected PPCPs ranged from 0.2 to 2437.9 ng/L. Higher concentrations of PPCPs were observed in spring and autumn, which were mainly attributed to seasonal differences in PPCP consumption. Generally, pollution level was higher in industry and agriculture area and in the inner bay and southwest of Taihu Lake. Source apportionment indicated that untreated water was the main source of PPCPs in river waters of the northern TLB. Flux estimation showed that the mean annual flux of PPCPs from northern TLB to Taihu Lake in 2021 was 1.6 t/a, which was higher in comparison with other areas. Overall, the resulting data will be useful to enrich the research of PPCPs in freshwater for environmental investigations.